Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2749165 | 1.00 | CYP1A2 (0.49) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL22338688 | 0.84 | CYP1A2 (0.40) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL1477358 | 0.82 | GRM5 (0.51) | CYP11B1CYP11B2CYP3A4CYP3A5CHRNB2 | |
| SCHEMBL22303444 | 0.81 | CYP11B2 (0.41) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL23136077 | 0.80 | CYP1A2 (0.38) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL9765843 | 0.80 | FKBP5 (0.42) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL20448751 | 0.79 | CYP11B2 (0.38) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL9967844 | 0.79 | KIF11 (0.44) | CYP1A2METAP2CYP11B1CYP11B2KIF11 | |
| SCHEMBL16894199 | 0.78 | KIF11 (0.62) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL1476263 | 0.78 | CHRNB2 (0.57) | CYP3A4CYP3A5GRIN1GRIN2BCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-119330972-A | PARP7 inhibitor and application thereof | 重庆华森英诺生物科技有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-117279917-A | Piperazine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |