Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133235 | 0.80 | CYP1A2 (0.49) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL2749165 | 0.80 | CYP1A2 (0.49) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL11263619 | 0.76 | FKBP5 (0.42) | FKBP5CYP11B1CYP11B2XDHPIK3CA | |
| SCHEMBL1477358 | 0.71 | GRM5 (0.51) | CYP11B1CYP11B2CYP3A4CYP3A5CHRNB2 | |
| SCHEMBL1476263 | 0.68 | CHRNB2 (0.57) | CYP3A4CYP3A5GRIN1GRIN2BCHRNB2 | |
| SCHEMBL1477141 | 0.67 | GRM5 (0.50) | CYP11B1CYP11B2CHRNB2CHRNA4TAS2R14 | |
| Water SCHEMBL14333714 | 0.67 | — | — | |
| SCHEMBL22338688 | 0.67 | CYP1A2 (0.40) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL20448751 | 0.66 | CYP11B2 (0.38) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL16894199 | 0.65 | KIF11 (0.62) | CYP1A2METAP2CYP11B1CYP11B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |