Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827037 | 0.80 | KMT2A (0.41) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL12045381 | 0.73 | ACVRL1 (0.43) | CYP3A4ADORA3ADORA2A | |
| SCHEMBL30143562 | 0.72 | HTR7 (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL1149992 | 0.71 | HPGD (0.65) | MEN1KMT2AMAPTRECQLCYP3A4 | |
| SCHEMBL26102654 | 0.70 | HPGD (0.51) | MEN1KMT2AMAPTHPGD | |
| SCHEMBL30143567 | 0.70 | KMT2A (0.50) | MEN1KMT2AHPGDCA12CA1 | |
| SCHEMBL27520534 | 0.67 | HPGD (0.36) | MAPTRECQLNAMPTCYP3A4HPGD | |
| SCHEMBL21733177 | 0.66 | SIGMAR1 (0.35) | MEN1KMT2AMAPTCYP3A4ADORA3 | |
| SCHEMBL14560232 | 0.66 | BMPR1B (0.46) | CYP3A4 | |
| SCHEMBL13125709 | 0.65 | SIGMAR1 (0.40) | CYP3A4ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703798-A | Azaindolinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |