Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30144695 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| SCHEMBL8705170 | 0.82 | PTGS2 (0.52) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| SCHEMBL30877921 | 0.82 | PTGS2 (0.52) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| SCHEMBL30144760 | 0.82 | PTGS2 (0.52) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| SCHEMBL8705175 | 0.82 | PTGS2 (0.52) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| SCHEMBL8653245 | 0.80 | PTGS2 (0.54) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| Cyclohexanol SCHEMBL11330945 | 0.77 | TSHR (0.59) | TSHRSLC18A3ALDH1A1LMNASMN1; SMN2 | |
| Biphenyl SCHEMBL28053113 | 0.75 | ALDH1A1 (0.50) | TSHRSLC18A3ALDH1A1MEN1KMT2A | |
| SCHEMBL8518215 | 0.75 | PTGS2 (0.59) | SLC6A2SLC6A4SLC6A3FGF23PTGS2 | |
| Biphenyl SCHEMBL28893342 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515588-A | Macrocyclic ULK1/2 inhibitors | 萨克生物研究学院 | 2022-12-23 | — | — | CN | disclosed |