SCHEMBL8705175

SCHEMBL8705175

c1ccc(C2=C(c3ccccc3)CCCCCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.52
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
FGF23 Q9GZV9 1/20 0.47
CFTR P13569 1/20 0.46
GOPC Q9HD26 1/20 0.46
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.38
PTGS1 P23219 1/20 0.37
MAPK14 Q16539 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8705170 1.00 PTGS2 (0.52) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL30144760 1.00 PTGS2 (0.52) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL30877921 1.00 PTGS2 (0.52) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL8653245 0.97 PTGS2 (0.54) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL8518215 0.91 PTGS2 (0.59) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL7212942 0.84 ALDH1A1 (0.53) PTGS2FGF23CFTRGOPCCHRNB4
SCHEMBL27874435 0.83 KMT2A (0.46) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL5606620 0.83 PTGS2 (0.53) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL29681890 0.83 SLC6A2 (0.46) PTGS2SLC6A2SLC6A4SLC6A3FGF23
SCHEMBL30144692 0.82 SLC6A2 (0.42) PTGS2SLC6A2SLC6A4SLC6A3FGF23

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119792395-A Pharmaceutical composition and application thereof 上海黄海制药有限责任公司 2025-04-11 CN claimed
CN-119607064-A Application of pharmaceutical composition in prevention and treatment of pulmonary diseases 上海黄海制药有限责任公司 2025-03-14 CN claimed
CN-118652291-A Two biphenyl cyclooctene lignans, extraction method and application thereof 陕西省西安植物园(陕西省植物研究所) 2024-09-17 CN claimed
CN-117890603-A Application of PD-L1 as drug target in screening drugs for inhibiting tendon adhesion 南通大学附属医院 2024-04-16 CN claimed
CN-117180264-B Application of schisandrin B in preparing analgesic Mengyang Pharmaceutical (Shanghai) Co.,Ltd. (CN) 2026-05-26 CN disclosed
CN-119950490-A Application of schisandrin B in sensitization of 5-fluorouracil for treating colorectal cancer 中国人民解放军海军军医大学第二附属医院 2025-05-09 CN disclosed
CN-119876062-A Polypeptide for catalyzing lignan cyclization, encoding gene, preparation method and application 中国医学科学院药用植物研究所 2025-04-25 CN disclosed
CN-119818560-A Caulis Spatholobi extract and its preparation method, cyclodextrin clathrate compound containing the same, pharmaceutical composition and pharmaceutical preparation 北京中医药大学 2025-04-15 CN disclosed
CN-119656150-A Application of aryl schisandra chinensis phenolic ester in preparation of medicament for treating depression and prepared antidepressant medicament 中国医学科学院药物研究所 2025-03-21 CN disclosed
CN-119632198-A Multi-vitamin nutritional composition containing compound protein peptide and preparation method of multi-vitamin nutritional composition 湃耐尔(黑龙江)饮品有限公司 2025-03-18 CN disclosed
CN-119607064-A Application of pharmaceutical composition in prevention and treatment of pulmonary diseases 上海黄海制药有限责任公司 2025-03-14 CN disclosed
CN-119139278-A Biphenyl cyclooctene lignans application of compound and chemosensitization medicine 广州中医药大学(广州中医药研究院) 2024-12-17 CN disclosed
CN-117180264-A Application of schisandrin B in preparing analgesic 梦阳药业(上海)有限公司 2023-12-08 CN disclosed
CN-116606832-A Dibenzylbutane lignan oxymethyl transferase and application thereof 中国医学科学院药用植物研究所 2023-08-18 CN disclosed
CN-116478949-A Lignan oxymethyl transferase and use thereof 中国医学科学院药用植物研究所 2023-07-25 CN disclosed
CN-116478949-A Lignan oxymethyl transferase and use thereof 中国医学科学院药用植物研究所 2023-07-25 CN disclosed
CN-116445443-A Bibenzocyclooctene lignan oxymethyl transferase and application thereof 中国医学科学院药用植物研究所 2023-07-18 CN disclosed
CN-116239454-A Method for simultaneously preparing schizandrin A and schizandrin A from kadsura longepedunculata 上海长征医院 2023-06-09 CN disclosed
CN-116115601-A Application of gomisin E in preparation of cardiovascular disease drugs 中国医学科学院药物研究所 2023-05-16 CN disclosed
WO-1998049128-A1 PROCESS FOR PREPARING A (HETERO)AROMATIC OLEFIN DSM N.V. (NL) 1998-11-05 WO disclosed