Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705170 | 1.00 | PTGS2 (0.52) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL30877921 | 1.00 | PTGS2 (0.52) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL8705175 | 1.00 | PTGS2 (0.52) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL8653245 | 0.97 | PTGS2 (0.54) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL8518215 | 0.91 | PTGS2 (0.59) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL7212942 | 0.84 | ALDH1A1 (0.53) | PTGS2FGF23CFTRGOPCCHRNB4 | |
| SCHEMBL27874435 | 0.83 | KMT2A (0.46) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL5606620 | 0.83 | PTGS2 (0.53) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL29681890 | 0.83 | SLC6A2 (0.46) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 | |
| SCHEMBL30144692 | 0.82 | SLC6A2 (0.42) | PTGS2SLC6A2SLC6A4SLC6A3FGF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515588-A | Macrocyclic ULK1/2 inhibitors | 萨克生物研究学院 | 2022-12-23 | — | — | CN | disclosed |