SCHEMBL30144797

SCHEMBL30144797

CC(=O)c1cccc2cccnc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.68
NPC1 O15118 3/20 0.60
RAB9A P51151 2/20 0.60
CASP3 P42574 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
ALDH1A1 P00352 5/20 0.57
LMNA P02545 2/20 0.54
ALOX12 P18054 2/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MMP2 P08253 2/20 0.52
TSHR P16473 2/20 0.52
CHRM1 P11229 1/20 0.52
COMT P21964 1/20 0.52
ADRA1A P35348 1/20 0.52
METAP2 P50579 1/20 0.52
METAP1 P53582 1/20 0.52
HDAC8 Q9BY41 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632726 1.00 PARP1 (0.68) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL1765845 0.84 PARP1 (0.61) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL28050846 0.84 PARP1 (0.72) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL111826 0.82 PARP1 (0.70) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL29749881 0.82 PARP1 (0.70) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL9701377 0.81 PARP1 (0.58) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL15866503 0.81 PARP1 (0.68) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL460456 0.81 PARP1 (1.00) PARP1NPC1RAB9ACASP3SENP8
Hydrochloric Acid SCHEMBL7320778 0.81 PARP1 (0.68) PARP1NPC1RAB9ACASP3SENP8
SCHEMBL4507521 0.81 PARP1 (0.68) PARP1NPC1RAB9ACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP disclosed
US-12187741-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2025-01-07 US disclosed
CN-113710662-B Heterocyclic compound and organic light-emitting device including the same LT素材株式会社 2024-06-18 CN disclosed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO disclosed
US-20220411440-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411440-A1 GLYCOSIDASE INHIBITORS GAA, ENGASE, GBA3 PARP1 1179/4885NPC1 386/4885RAB9A 730/4885
US-12187741-B2 Glycosidase inhibitors GAA, ENGASE, GBA3 PARP1 1179/4885NPC1 386/4885RAB9A 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.