Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940676 | 1.00 | AXL (0.36) | AXLPRKCIGOT1LMNAMAPT | |
| SCHEMBL738011 | 0.78 | AXL (0.34) | AXLPRKCIGOT1MAPTTDP1 | |
| SCHEMBL21598402 | 0.78 | NOS2 (0.39) | AXLPRKCIGOT1MAPTTDP1 | |
| SCHEMBL4486246 | 0.78 | AXL (0.34) | AXLPRKCIGOT1LMNAMAPT | |
| SCHEMBL741028 | 0.78 | GOT1 (0.33) | GOT1MAPTTDP1ALDH1A1ADORA3 | |
| SCHEMBL14691019 | 0.78 | AXL (0.34) | AXLPRKCIGOT1MAPTTDP1 | |
| SCHEMBL28576286 | 0.77 | KDM4E (0.41) | AXLPRKCILMNAMEN1KMT2A | |
| SCHEMBL4371682 | 0.74 | ALDH1A1 (0.36) | GOT1MAPTTDP1GAAPOLB | |
| SCHEMBL29661956 | 0.73 | — | — | |
| SCHEMBL385136 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |