SCHEMBL30148110

SCHEMBL30148110

CC(C)(C)OC(=O)N1CCCC1c1cncs1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
GPR119 Q8TDV5 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TSHR P16473 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
UCHL1 P09936 2/20 0.42
USP30 Q70CQ3 1/20 0.42
NPC1 O15118 1/20 0.41
LMNA P02545 2/20 0.41
BCL2 P10415 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27724525 0.94 GPR119 (0.44) ALDH1A1GPR119HSD17B10TSHRL3MBTL1
SCHEMBL29105048 0.83 PARP1 (0.41) ALDH1A1GPR119TSHRL3MBTL1MEN1
SCHEMBL21193363 0.80 HPGDS (0.47) ALDH1A1GPR119HSD17B10MEN1KMT2A
SCHEMBL29716174 0.80 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRL3MBTL1MEN1
SCHEMBL7505260 0.79 GPR119 (0.55) ALDH1A1GPR119HSD17B10MEN1KMT2A
SCHEMBL30563646 0.77 PKM (0.46) ALDH1A1GPR119HSD17B10TSHRL3MBTL1
SCHEMBL8121502 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRL3MBTL1MEN1
SCHEMBL19777235 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRL3MBTL1MEN1
SCHEMBL8105531 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRL3MBTL1MEN1
SCHEMBL6468031 0.76 ALDH1A1 (0.45) ALDH1A1GPR119TSHRL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710210-A Iron catalyzed amination of C-H bonds 港大科桥有限公司 2023-02-24 CN disclosed