Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 10/20 | 0.38 |
| ▸ | BRAF | P15056 | 10/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.32 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180862 | 0.85 | RORC (0.42) | RAF1BRAFMALT1BACE1 | |
| SCHEMBL30772208 | 0.85 | RORC (0.42) | RAF1BRAFMALT1BACE1 | |
| Hydrochloric Acid SCHEMBL29180786 | 0.84 | CYP17A1 (0.33) | RAF1BRAFMALT1 | |
| SCHEMBL24802440 | 0.81 | CYP17A1 (0.37) | SLC13A5SLC13A2SLC13A3 | |
| SCHEMBL30772165 | 0.78 | SCN9A (0.35) | RAF1 | |
| SCHEMBL24804886 | 0.78 | SCN9A (0.35) | RAF1 | |
| SCHEMBL30148717 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL29180832 | 0.76 | CYP11B2 (0.35) | — | |
| SCHEMBL22574269 | 0.74 | CYP11B2 (0.45) | PRMT5WDR77 | |
| SCHEMBL30772189 | 0.73 | KAT2B (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |