Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564494 | 0.68 | ALDH1A1 (0.49) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL10840036 | 0.66 | TSHR (0.48) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL29741801 | 0.66 | L3MBTL1 (0.41) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL8572316 | 0.66 | TSHR (0.57) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL994563 | 0.66 | RAB9A (0.55) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL10809546 | 0.65 | L3MBTL1 (1.00) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL3778015 | 0.64 | TSHR (0.68) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL2654505 | 0.64 | L3MBTL1 (0.59) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL7772250 | 0.63 | RAB9A (0.49) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 | |
| SCHEMBL2907201 | 0.63 | RAB9A (0.49) | L3MBTL1RAB9ATSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377298-A1 | PROTEIN SECRETION INHIBITORS | Gate Bioscience, Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |