Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158699 | 0.87 | ALDH1A1 (0.50) | P2RX7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL30158611 | 0.87 | ALDH1A1 (0.50) | P2RX7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL30158686 | 0.82 | MDM2 (0.38) | P2RX7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL30158586 | 0.80 | HCRTR2 (0.49) | P2RX7HCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL31705306 | 0.79 | KMT2A (0.48) | P2RX7HCRTR1HCRTR2 | |
| SCHEMBL30158747 | 0.78 | FFAR4 (0.43) | P2RX7PDE2APTGER4PTGER3PTGER2 | |
| SCHEMBL30158802 | 0.78 | P2RX7 (0.39) | P2RX7HCRTR1HCRTR2TSHR | |
| SCHEMBL30158884 | 0.78 | P2RX7 (0.54) | P2RX7ALDH1A1 | |
| SCHEMBL30158624 | 0.77 | HCRTR1 (0.52) | P2RX7HCRTR1HCRTR2 | |
| SCHEMBL30157534 | 0.76 | ALDH1A1 (0.41) | P2RX7ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |