SCHEMBL301595

SCHEMBL301595

Cc1cnc2c(O)cccc2c1.Cc1cnc2c(O)cccc2c1.[Al]Oc1ccccc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.62
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
PSMD14 O00487 1/20 0.42
COPS5 Q92905 1/20 0.42
PARP1 P09874 1/20 0.40
PAX8 Q06710 1/20 0.40
SLC40A1 Q9NP59 1/20 0.39
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
CYP1A2 P05177 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL6117507 0.79 METAP2 (0.59) KDM4EMEN1KMT2ACYP1A2LMNA
8-Hydroxy Quinaldine SCHEMBL3483081 0.79 METAP2 (0.59) KDM4EMEN1KMT2ACYP1A2LMNA
SCHEMBL1787225 0.79 KDM4E (1.00) KDM4ECCR1CCR5CCR8PSMD14
SCHEMBL17691560 0.77 CCR1 (0.60) KDM4ECCR1CCR5CCR8PSMD14
SCHEMBL27824094 0.77 KDM4E (0.96) KDM4ECCR1CCR5CCR8PSMD14
Hydrochloric Acid SCHEMBL9333864 0.77 KDM4E (0.96) KDM4ECCR1CCR5CCR8PSMD14
SCHEMBL28723725 0.70 KDM4E (1.00) KDM4EPARP1PAX8IDO1TDO2
SCHEMBL983135 0.69 MAPK1 (0.48) KDM4ELMNAMAPK1TDP1L3MBTL1
Oxyquinoline SCHEMBL28149590 0.69 METAP2 (0.57) KDM4ECCR1CCR5CCR8MEN1
Oxyquinoline SCHEMBL16857438 0.69 METAP2 (0.57) KDM4ECCR1CCR5CCR8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404976-B1 Organic material and organic light emitting device including the same SAMSUNG DISPLAY CO LTD (KR) 2014-06-25 EP disclosed
US-8512881-B2 Organic material and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-20 US disclosed
US-20120007495-A1 ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-12 US disclosed
EP-2404976-A2 Organic material and organic light emitting device including the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007495-A1 ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME OCIAD1, OLA1, OPRM1 KDM4E 1648/4885CCR1 537/4885CCR5 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.