SCHEMBL30160396

SCHEMBL30160396

O=C1Nc2ncc(Br)cc2CCC1N1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL4 Q8NA19 1/20 0.36
L3MBTL3 Q96JM7 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CRBN Q96SW2 4/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
DDB1 Q16531 2/20 0.34
OPRK1 P41145 1/20 0.34
HRH3 Q9Y5N1 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23532125 1.00 L3MBTL4 (0.36) L3MBTL4L3MBTL3L3MBTL1CRBNKDM4E
SCHEMBL23532161 0.90 SMYD3 (0.34) CRBNKDM4EALDH1A1DDB1
SCHEMBL30160267 0.90 SMYD3 (0.34) CRBNKDM4EALDH1A1DDB1
SCHEMBL23531925 0.89 ALDH1A1 (0.34) CRBNALDH1A1DDB1OPRK1KMT2A
SCHEMBL23532172 0.88 CRBN (0.33) CRBNDDB1
SCHEMBL18903202 0.86 KDM4E (0.35) L3MBTL4L3MBTL3L3MBTL1CRBNKDM4E
SCHEMBL23532067 0.86 FAAH (0.36)
SCHEMBL25198512 0.86 FAAH (0.36)
SCHEMBL30304205 0.85 CRBN (0.35) CRBNALDH1A1DDB1
SCHEMBL23532103 0.85 CRBN (0.34) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473283-B2 Compounds and their use DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-11-18 US disclosed
US-20240317740-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2024-09-26 US disclosed
EP-4077324-A1 NOVEL COMPOUNDS AND THEIR USE Debiopharm International SA (CH) 2022-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317740-A1 NOVEL COMPOUNDS AND THEIR USE PGLS, LSS, LAS1L L3MBTL4 387/4885L3MBTL3 311/4885L3MBTL1 237/4885
US-12473283-B2 Compounds and their use LSS, PGLS, LDHB L3MBTL4 235/4885L3MBTL3 152/4885L3MBTL1 125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.