Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802360 | 0.94 | NLRP3 (0.59) | NLRP3MYCXDHSLC22A12LNPEP | |
| SCHEMBL22802375 | 0.85 | NLRP3 (0.59) | NLRP3MYCXDHSLC22A12LNPEP | |
| Trifluoroacetic Acid SCHEMBL30163374 | 0.84 | NLRP3 (0.41) | NLRP3LNPEPRXRBRXRARXRG | |
| Trifluoroacetic Acid SCHEMBL30163366 | 0.82 | NLRP3 (0.54) | NLRP3SLC22A12LNPEPRXRBRXRA | |
| SCHEMBL30163238 | 0.82 | NLRP3 (0.54) | NLRP3MYCXDHSLC22A12LNPEP | |
| SCHEMBL22802381 | 0.82 | NLRP3 (0.54) | NLRP3MYCXDHSLC22A12LNPEP | |
| SCHEMBL22802363 | 0.77 | NLRP3 (0.44) | NLRP3LNPEPRXRBRXRARXRG | |
| SCHEMBL22802368 | 0.75 | NLRP3 (0.59) | NLRP3RXRBRXRARXRG | |
| SCHEMBL24922421 | 0.73 | NLRP3 (0.48) | NLRP3MYCXDHSLC22A12EED | |
| SCHEMBL20634909 | 0.73 | NLRP3 (0.45) | NLRP3MYCXDHSLC22A12EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030879-B2 | Sulfonyl acetamides as NLRP3 inhibitors | INFLAZOME LIMITED (IE) | 2024-07-09 | — | — | US | disclosed |
| US-11884645-B2 | Sulfonyl acetamides as NLRP3 inhibitors | INFLAZOME LIMITED (IE) | 2024-01-30 | — | — | US | disclosed |
| US-11834433-B2 | Compounds | INFLAZOME LIMITED (IE) | 2023-12-05 | — | — | US | disclosed |
| US-11530200-B2 | Compounds | INFLAZOME LIMITED (IE) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030879-B2 | Sulfonyl acetamides as NLRP3 inhibitors | NLRP3, NOD1, NLRP1 | NLRP3 1/4885MYC 4225/4885XDH 100/4885 |
| US-11884645-B2 | Sulfonyl acetamides as NLRP3 inhibitors | NLRP3, NOD1, ABCC5 | NLRP3 1/4885MYC 4177/4885XDH 105/4885 |
| US-11834433-B2 | Compounds | NLRP3, NOD1, PYCARD | NLRP3 1/4885MYC 2519/4885XDH 16/4885 |
| US-11530200-B2 | Compounds | NLRP3, NOD1, NLRP1 | NLRP3 1/4885MYC 2959/4885XDH 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.