Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689466 | 0.82 | KDM4E (0.55) | LMNATDP1ALDH1A1SMN1; SMN2NOTUM | |
| SCHEMBL9922005 | 0.79 | LMNA (0.53) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL676142 | 0.79 | LMNA (0.82) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL30535283 | 0.79 | LMNA (0.82) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL4130798 | 0.78 | LMNA (0.56) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| Potassium SCHEMBL6776357 | 0.77 | LMNA (0.78) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL14022002 | 0.77 | SMN1; SMN2 (0.53) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL170884 | 0.76 | LMNA (0.75) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL779090 | 0.75 | LMNA (0.53) | LMNATDP1ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL9487846 | 0.74 | LTA4H (0.52) | SMN1; SMN2HTTLTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363417-A1 | PYRROLOPYRIDONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Tay Therapeutics Limited (GB) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023275542-A1 | PYRROLOPYRIDONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Tay Therapeutics Limited (GB) | 2023-01-05 | — | — | WO | disclosed |