Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133572 | 0.90 | TGFBR1 (0.53) | LMNATDP1SMN1; SMN2ALDH1A1TGFBR1 | |
| SCHEMBL11573009 | 0.84 | ALDH1A1 (0.59) | LMNATDP1SMN1; SMN2ALDH1A1TGFBR1 | |
| SCHEMBL4796671 | 0.79 | LMNA (0.49) | LMNATDP1SMN1; SMN2ALDH1A1TGFBR1 | |
| SCHEMBL30163333 | 0.78 | LMNA (0.60) | LMNATDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11208196 | 0.77 | MAPK1 (0.58) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL11457992 | 0.76 | LMNA (0.81) | LMNATDP1SMN1; SMN2ALDH1A1TGFBR1 | |
| SCHEMBL162478 | 0.76 | — | — | |
| SCHEMBL29441943 | 0.76 | — | — | |
| SCHEMBL4130236 | 0.76 | LMNA (0.62) | LMNATDP1SMN1; SMN2ALDH1A1TGFBR1 | |
| SCHEMBL30535283 | 0.76 | LMNA (0.82) | LMNATDP1SMN1; SMN2ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |