Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428775 | 0.83 | FKBP1A (0.69) | ALDH1A1FKBP1AKDM4ETSHRL3MBTL1 | |
| SCHEMBL5692416 | 0.82 | ALDH1A1 (0.77) | ALDH1A1FKBP1AKDM4ETSHRMAPT | |
| SCHEMBL31428602 | 0.81 | ALDH1A1 (1.00) | ALDH1A1FKBP1AKDM4EMAPTHTT | |
| SCHEMBL5692309 | 0.81 | ALDH1A1 (1.00) | ALDH1A1FKBP1AKDM4EMAPTHTT | |
| SCHEMBL31428466 | 0.79 | ALDH1A1 (0.46) | ALDH1A1FKBP1AKDM4ETSHRL3MBTL1 | |
| SCHEMBL528448 | 0.77 | ALDH1A1 (0.72) | ALDH1A1FKBP1AKDM4EL3MBTL1MAPT | |
| SCHEMBL7316803 | 0.77 | FKBP1A (0.67) | ALDH1A1FKBP1ATSHRL3MBTL1MAPT | |
| SCHEMBL5692472 | 0.76 | ALDH1A1 (1.00) | ALDH1A1FKBP1AKDM4EL3MBTL1MAPT | |
| SCHEMBL3630046 | 0.74 | ALDH1A1 (0.60) | ALDH1A1FKBP1AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8320871 | 0.73 | ALDH1A1 (0.79) | ALDH1A1FKBP1AKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885FKBP1A 2064/4885KDM4E 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.