Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428602 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A | |
| SCHEMBL5692309 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A | |
| SCHEMBL5692383 | 0.86 | KDM4E (0.61) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL30163498 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A | |
| SCHEMBL5692472 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A | |
| SCHEMBL5066050 | 0.79 | LMNA (0.60) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL5692621 | 0.79 | POLB (0.56) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL528448 | 0.78 | ALDH1A1 (0.72) | ALDH1A1KDM4ESMN1; SMN2FKBP1AKMT2A | |
| SCHEMBL5692506 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A | |
| SCHEMBL5692515 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAASMN1; SMN2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281789-A1 | Protein kinase inhibitors | KYOWA HAKKO KOGYO CO., LTD (JP) | 2006-12-14 | — | — | US | disclosed |
| EP-1650194-A1 | PROTEIN KINASE INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281789-A1 | Protein kinase inhibitors | MAP3K20, MAP3K1, MAP3K19 | ALDH1A1 2999/4885KDM4E 1355/4885GAA 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.