Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026867 | 0.88 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10JMJD6 | |
| SCHEMBL3029297 | 0.85 | P2RX7 (0.33) | KDM4EALDH1A1HPGDHSD17B10P2RX7 | |
| SCHEMBL3027169 | 0.80 | LMNA (0.43) | KDM4EALDH1A1HPGDHSD17B10JMJD6 | |
| SCHEMBL3021431 | 0.76 | SMN1; SMN2 (0.37) | KDM4EALDH1A1JMJD6KMT2ALMNA | |
| SCHEMBL3024261 | 0.75 | SMN1; SMN2 (0.34) | KDM4EALDH1A1JMJD6KMT2ALMNA | |
| SCHEMBL3122877 | 0.73 | — | — | |
| SCHEMBL16386042 | 0.72 | CMA1 (0.42) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3033797 | 0.70 | KDM4E (0.33) | KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL3030386 | 0.69 | KDM4E (0.33) | KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL21723595 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1JMJD6KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802713-B2 | 3-alkoxy-1-phenylpyrazole derivatives and pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2202226-B1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2202226-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | Kumiai Chemical Industry CO., LTD. (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | HCN3, HCN4, KCNH3 | KDM4E 350/4885ALDH1A1 1571/4885HPGD 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.