Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25529069 | 1.00 | L3MBTL1 (0.47) | L3MBTL1POLBTDP1CTDSP1PTPN1 | |
| SCHEMBL30174176 | 0.87 | L3MBTL1 (0.42) | L3MBTL1POLBTDP1CTDSP1ADORA3 | |
| SCHEMBL25529098 | 0.76 | KMT2A (0.39) | L3MBTL1POLBTDP1KDM4EKMT2A | |
| SCHEMBL25544889 | 0.75 | PTPN1 (0.51) | L3MBTL1POLBTDP1PTPN1ADORA3 | |
| SCHEMBL30367543 | 0.72 | LMNA (0.45) | KDM4EKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL18920540 | 0.71 | MYC (0.53) | L3MBTL1POLBTDP1CTDSP1PTPN1 | |
| SCHEMBL11780649 | 0.71 | ADORA3 (0.51) | L3MBTL1POLBTDP1ADORA3KDM4E | |
| SCHEMBL25234719 | 0.70 | DHODH (0.40) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30174258 | 0.70 | DHODH (0.40) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30174280 | 0.70 | IKBKB (0.43) | L3MBTL1TDP1PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |