Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25529069 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ADORA3ADORA2AADORA1POLB | |
| SCHEMBL30174268 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ADORA3ADORA2AADORA1POLB | |
| SCHEMBL28966253 | 0.79 | ALDH1A1 (0.42) | L3MBTL1POLBTDP1ALDH1A1GLA | |
| SCHEMBL30174280 | 0.77 | IKBKB (0.43) | L3MBTL1ADORA2BIKBKBTDP1ALDH1A1 | |
| SCHEMBL30174251 | 0.77 | L3MBTL1 (0.57) | L3MBTL1ADORA3ADORA1IKBKBPOLB | |
| SCHEMBL30174256 | 0.76 | ALOX5 (0.37) | L3MBTL1POLBTDP1ALDH1A1GLA | |
| SCHEMBL30174255 | 0.75 | SLC2A1 (0.38) | POLBTDP1 | |
| SCHEMBL30174236 | 0.75 | EEF2K (0.38) | L3MBTL1POLBTDP1ALDH1A1GLA | |
| SCHEMBL18920575 | 0.73 | KEAP1 (0.44) | L3MBTL1IKBKBPOLBTDP1CTDSP1 | |
| SCHEMBL29812284 | 0.72 | LMNA (0.44) | IKBKBTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |