SCHEMBL30175769

SCHEMBL30175769

NC(=O)CCNC(=O)OC[C@H](N)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.49
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SLC1A3 P43003 1/20 0.44
SLC1A1 P43005 1/20 0.44
EPHX1 P07099 1/20 0.43
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41
MME P08473 1/20 0.41
ACE P12821 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30175773 1.00 MMP2 (0.49) MMP2HTTLMNASMN1; SMN2SLC1A3
SCHEMBL30175830 0.86 MMP2 (0.49) MMP2SMN1; SMN2EPHX1ALPIPKM
SCHEMBL30175755 0.86 MMP2 (0.49) MMP2SMN1; SMN2EPHX1ALPIPKM
SCHEMBL30175749 0.86 MMP2 (0.49) MMP2SMN1; SMN2EPHX1ALPIPKM
SCHEMBL11947655 0.84 POLB (0.54) MMP2HTTLMNASMN1; SMN2SLC1A3
SCHEMBL17045235 0.82 MMP2 (0.51) MMP2EPHX1ALPIPKMPTGS1
SCHEMBL11947656 0.82 MMP2 (0.51) MMP2EPHX1ALPIPKMPTGS1
SCHEMBL17045233 0.82 MMP2 (0.51) MMP2EPHX1ALPIPKMPTGS1
SCHEMBL11947652 0.82 REN (0.50) MMP2HTTLMNA
Solriamfetol SCHEMBL30929348 0.82 PKM (0.56) MMP2LMNASMN1; SMN2SLC1A3SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US claimed
US-20240358668-A1 METHODS AND COMPISITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCUALR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-10-31 US disclosed
EP-4395763-A1 METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE AXSOME THERAPEUTICS (US) 2024-07-10 EP disclosed
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US disclosed
WO-2023034944-A1 METHODS AND COMPOSITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCULAR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE AXSOME THERAPEUTICS (US) 2023-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358668-A1 METHODS AND COMPISITIONS FOR AMELIORATING BIOMARKERS ASSOCIATED WITH CARDIOVASCUALR RISK USING (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE FABP3, CPB2, TNNI3 MMP2 1599/4885HTT 1739/4885LMNA 725/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 MMP2 2633/4885HTT 991/4885LMNA 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.