Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11909114 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTL3MBTL1SLC9A1 | |
| SCHEMBL30175832 | 0.77 | SLC9A1 (0.66) | ALDH1A1HPGDMAPTL3MBTL1SLC9A1 | |
| SCHEMBL4944722 | 0.76 | ALDH1A1 (0.77) | ALDH1A1HPGDMAPTL3MBTL1SLC9A1 | |
| SCHEMBL5151601 | 0.75 | LMNA (0.57) | ALDH1A1MAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL30175775 | 0.74 | ABCB1 (0.54) | ALDH1A1HPGDMAPTL3MBTL1KDM4E | |
| SCHEMBL30175837 | 0.73 | SMARCA2 (0.50) | ALDH1A1MAPTL3MBTL1SLC9A1KDM4E | |
| SCHEMBL7748877 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTL3MBTL1KDM4E | |
| SCHEMBL10438816 | 0.73 | HTR7 (0.53) | ALDH1A1HPGDMAPTKDM4ERAB9A | |
| SCHEMBL12140121 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTL3MBTL1KDM4E | |
| SCHEMBL27996376 | 0.72 | KMT2A (0.59) | ALDH1A1MAPTL3MBTL1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034813-A1 | AN EIF4A INHIBITOR WITH A NOVEL MECHANISM OF ACTION | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-03-09 | — | — | WO | disclosed |