Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177265 | 0.86 | MGLL (0.46) | MGLLPRMT5WDR77OPRD1OPRK1 | |
| SCHEMBL8922008 | 0.79 | CHRM4 (0.59) | PRMT5WDR77CHRM4CHRM1CHRM2 | |
| SCHEMBL23867994 | 0.79 | MGLL (0.49) | MGLLSCD5 | |
| SCHEMBL23867975 | 0.79 | MGLL (0.49) | MGLLSCD5 | |
| SCHEMBL23868059 | 0.79 | MGLL (0.49) | MGLLSCD5 | |
| SCHEMBL29469966 | 0.79 | MGLL (0.49) | MGLLSCD5 | |
| SCHEMBL25410242 | 0.78 | CHRM1 (0.33) | MGLLCHRM4CHRM1CHRM2S1PR3 | |
| SCHEMBL23859672 | 0.77 | MGLL (0.57) | MGLLCHRM4CHRM1SCD5 | |
| SCHEMBL4709679 | 0.77 | PRMT5 (0.64) | PRMT5WDR77CHRM4CHRM1CHRM2 | |
| SCHEMBL30177254 | 0.77 | SMN1; SMN2 (0.43) | OPRD1OPRK1CHRM4CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126852-A1 | AZASPIROCYCLES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |