Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870765 | 0.86 | DRD4 (0.40) | ALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL30178331 | 0.85 | ALDH1A1 (0.56) | GPR119ALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL28644008 | 0.85 | LMNA (0.35) | GPR119ALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL30178376 | 0.85 | GPR119 (0.46) | GPR119ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL1814017 | 0.83 | KDM4E (0.48) | GPR119ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL19873705 | 0.80 | HTR4 (0.39) | KDM4ELMNA | |
| SCHEMBL16616311 | 0.79 | ALDH1A1 (0.47) | GPR119ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL3166766 | 0.76 | GPR119 (0.48) | GPR119ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL17803256 | 0.76 | USP30 (0.48) | GPR119ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2604335 | 0.75 | KDM4E (0.53) | GPR119ALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |