Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24843680 | 0.83 | ESR1 (0.51) | POLBESR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1155881 | 0.73 | ALDH1A1 (0.42) | POLBALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL16203677 | 0.67 | PTGS1 (0.51) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL17077928 | 0.67 | — | — | |
| SCHEMBL11964124 | 0.65 | LMNA (0.38) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL31309882 | 0.65 | PTGS1 (0.49) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL24581267 | 0.65 | PTGS1 (0.49) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL30963644 | 0.65 | PTGS1 (0.49) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8516519 | 0.64 | TLR8 (0.50) | POLBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL10070297 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278456-A2 | PYRIMIDINE-COMPLIANT PEPTIDE NUCLEIC ACID COMPOSITIONS AND METHODS OF USE THEREOF | NEUBASE THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |