Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179415 | 0.83 | PSMB1 (0.44) | ESR1MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1155881 | 0.81 | ALDH1A1 (0.42) | MAPTPOLBHDAC6ALDH1A1MEN1 | |
| SCHEMBL17077928 | 0.75 | — | — | |
| SCHEMBL11964124 | 0.73 | LMNA (0.38) | MAPTSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL8516519 | 0.71 | TLR8 (0.50) | MAPTSMN1; SMN2POLBTBXAS1L3MBTL1 | |
| SCHEMBL10070297 | 0.71 | — | — | |
| SCHEMBL28424796 | 0.70 | ESR1 (0.58) | ESR1MAPTSMN1; SMN2EGLN3PARP1 | |
| SCHEMBL21855432 | 0.70 | PSMB1 (0.62) | ESR1MAPTSMN1; SMN2EGLN3PARP1 | |
| SCHEMBL18934385 | 0.70 | CDA (0.36) | MAPT | |
| SCHEMBL2127227 | 0.70 | MTNR1A (0.62) | ESR1MAPTSMN1; SMN2EGLN3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278456-A2 | PYRIMIDINE-COMPLIANT PEPTIDE NUCLEIC ACID COMPOSITIONS AND METHODS OF USE THEREOF | NEUBASE THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |