Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763598 | 1.00 | DYRK1A (0.38) | DYRK1AADORA2AMAPK1JAK2PDPK1 | |
| SCHEMBL6358084 | 0.75 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL14906033 | 0.71 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL30876173 | 0.71 | MAPK1 (0.35) | MAPK1KDM4ECCNB2CDK1CCNB1 | |
| SCHEMBL3950985 | 0.71 | PDPK1 (0.38) | DYRK1AMAPK1PDPK1CCNB2CDK1 | |
| SCHEMBL30316980 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL30988525 | 0.70 | MAPK1 (0.46) | DYRK1AMAPK1JAK2PDPK1CYP3A4 | |
| SCHEMBL12467739 | 0.69 | DYRK1A (0.37) | DYRK1AMAPK1PDPK1 | |
| SCHEMBL16946863 | 0.69 | DYRK1A (0.37) | DYRK1APDPK1GAA | |
| SCHEMBL1495296 | 0.68 | PDPK1 (0.48) | PDPK1KDM4ECYP3A4GAAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-4114837-A1 | PYRAZOLOPYRAZINES ACTING ON CANCERS VIA INHIBITION OF CDK12 | Bayer Aktiengesellschaft (DE) | 2023-01-11 | — | — | EP | disclosed |