Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 9/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20047742 | 0.82 | IDO1 (0.50) | METAP2CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL23525615 | 0.80 | CCR1 (0.56) | HSD17B1HSD17B2METAP2CYP3A4CYP2C9 | |
| SCHEMBL30610284 | 0.80 | CCR1 (0.56) | HSD17B1HSD17B2METAP2CYP3A4CYP2C9 | |
| SCHEMBL15888400 | 0.79 | IDO1 (0.47) | BRAFCYP11B1CYP11B2ESR2 | |
| SCHEMBL14189372 | 0.78 | PARP1 (0.49) | CHEK1FYNCYP11B2PIK3CA | |
| SCHEMBL2614938 | 0.77 | RAB9A (0.47) | CYP11B1CYP11B2CYP1A2CYP2A6 | |
| SCHEMBL2614939 | 0.76 | IDO1 (0.51) | CYP11B1CYP11B2PIK3CGPIK3CACYP3A4 | |
| SCHEMBL30186373 | 0.74 | HSD17B1 (0.79) | FYNHSD17B1HSD17B2METAP2PIK3CG | |
| SCHEMBL28636416 | 0.74 | HSD17B2 (0.52) | HSD17B1HSD17B2METAP2CYP3A4CYP2C9 | |
| SCHEMBL17463151 | 0.74 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP3A4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522597-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | CHEK1 2710/4885FYN 1417/4885HSD17B1 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.