SCHEMBL30189574

SCHEMBL30189574

O=c1ccoc2ccc(Br)c(Br)c12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.41
MAOA P21397 7/20 0.41
FTO Q9C0B1 2/20 0.39
CYP19A1 P11511 1/20 0.35
ACHE P22303 1/20 0.33
DYRK1A Q13627 1/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.31
NFKB1 P19838 1/20 0.31
KCNA3 P22001 1/20 0.31
PTPRC P08575 1/20 0.31
HTR1A P08908 1/20 0.30
CYP2D6 P10635 1/20 0.30
SLC6A4 P31645 1/20 0.30
GRM5 P41594 1/20 0.30
ALOX5 P09917 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29008528 0.76 ALOX5 (0.31) ALOX5
SCHEMBL30189618 0.71 CYP19A1 (0.50) MAOBMAOAFTOCYP19A1KDM4E
SCHEMBL30189616 0.71 MAOB (0.40) MAOBMAOAFTOCYP19A1ACHE
SCHEMBL7680403 0.70 MAOB (0.45) MAOBMAOAFTOCYP19A1ACHE
SCHEMBL30189525 0.68 ALDH1A1 (0.35) MAOBMAOAFTOCYP19A1KDM4E
SCHEMBL1421578 0.68 MAOA (0.49) MAOBMAOAFTOACHEDYRK1A
SCHEMBL486181 0.65 MAOA (0.55) MAOBMAOAFTOKDM4ELMNA
SCHEMBL28632877 0.65 DYRK1A (0.37) MAOBMAOAFTOACHEDYRK1A
SCHEMBL11412674 0.65 MAOB (0.50) MAOBMAOAFTOACHEKDM4E
SCHEMBL27203827 0.64 MAOB (0.38) MAOBMAOAFTOACHEDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023373-A Luminescent material, application thereof and organic electroluminescent device comprising luminescent material 清华大学 2023-04-28 CN disclosed
CN-115636819-A Luminescent material, application thereof and organic electroluminescent device comprising luminescent material 清华大学 2023-01-24 CN disclosed