SCHEMBL7680403

SCHEMBL7680403

O=c1ccoc2ccoc(=O)c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.45
MAOA P21397 5/20 0.45
FTO Q9C0B1 2/20 0.45
KDM4E B2RXH2 4/20 0.36
DYRK1A Q13627 1/20 0.36
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
ACHE P22303 2/20 0.33
KCNA3 P22001 1/20 0.33
GRM5 P41594 1/20 0.33
ALOX5 P09917 1/20 0.33
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
CYP19A1 P11511 1/20 0.32
NFKB1 P19838 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11412674 0.71 MAOB (0.50) MAOBMAOAFTOKDM4ELMNA
SCHEMBL546446 0.70 MAOB (0.48) MAOBMAOAFTOKDM4ELMNA
SCHEMBL1421578 0.70 MAOA (0.49) MAOBMAOAFTOKDM4EDYRK1A
SCHEMBL30111795 0.70 HTR2B (0.50) MAOBMAOAFTOKDM4EMAPK1
SCHEMBL29568413 0.70 MAOB (0.48) MAOBMAOAFTOKDM4ELMNA
SCHEMBL30189574 0.70 MAOB (0.41) MAOBMAOAFTOKDM4EDYRK1A
SCHEMBL10504356 0.70 MAOB (0.48) MAOBMAOAFTOKDM4EDYRK1A
SCHEMBL29960477 0.70 AR (0.49) MAOBMAOAFTOKDM4ELMNA
SCHEMBL486181 0.67 MAOA (0.55) MAOBMAOAFTOKDM4ELMNA
SCHEMBL28632877 0.67 DYRK1A (0.37) MAOBMAOAFTOKDM4EDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420569-B1 Process for producing pyrone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-16 US disclosed