SCHEMBL486181

SCHEMBL486181

O=c1ccoc2ccc3ccccc3c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
FTO Q9C0B1 1/20 0.55
AHR P35869 5/20 0.53
PAX8 Q06710 2/20 0.53
ABCG2 Q9UNQ0 2/20 0.53
CYP1A1 P04798 1/20 0.53
CYP1A2 P05177 1/20 0.53
FYN P06241 1/20 0.53
MAPK3 P27361 1/20 0.53
POLB P06746 1/20 0.51
PTPN1 P18031 1/20 0.51
MAPT P10636 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7452979 0.93 MAOA (0.52) MAOAMAOBFTOAHRPAX8
SCHEMBL1866520 0.77 MTNR1A (0.48) MAOAMAOBFTOAHRPAX8
SCHEMBL30423508 0.77 MTNR1A (0.48) MAOAMAOBFTOAHRPAX8
SCHEMBL28776994 0.76 L3MBTL1 (0.51) MAOAMAOBFTOAHRPAX8
SCHEMBL420462 0.74 ALDH1A1 (0.55) MAOAMAOBFTOPAX8POLB
SCHEMBL30716378 0.74 ALDH1A1 (0.55) MAOAMAOBFTOPAX8POLB
SCHEMBL7918673 0.73 PAX8 (0.56) AHRPAX8ABCG2CYP1A1CYP1A2
SCHEMBL1421578 0.73 MAOA (0.49) MAOAMAOBFTOCYP1A1CYP1A2
SCHEMBL7912365 0.72 ABCG2 (0.60) MAOAAHRPAX8ABCG2CYP1A1
SCHEMBL27810763 0.72 ALDH1A1 (0.52) MAOAMAOBFTOPAX8POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-112996799-B Composition for neuroprotection comprising naphthopyranone derivative derived from cassia bud 韩国科学技术研究院 2025-02-07 CN claimed
WO-2024192348-A2 METHODS OF TREATING HPV IN HIV-INFECTED PATIENTS OHIO STATE INNOVATION FOUNDATION (US) 2024-09-19 WO claimed
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2024-04-18 US claimed
CN-117813004-A Auxin herbicide and application method thereof 科迪华农业科技有限责任公司 2024-04-02 CN claimed
US-11672866-B2 Osteotropic nanoparticles for prevention or treatment of bone metastases UNM RAINFOREST INNOVATIONS 2023-06-13 US claimed
CN-116124746-A Application of naphthobenzopyrone fluorescent probe in detection of mercury ions, iron ions and iodide ions 甘肃中医药大学 2023-05-16 CN claimed
WO-2023040090-A1 DINAPHTHO R-PYRONE COMPOUNDS AND APPLICATION THEREOF AGAINST PLANT ANTHRACNOSE 中国热带农业科学院热带作物品种资源研究所 2023-03-23 WO claimed
EP-2967035-B1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING PYRIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR USE IN CORN (MAIZE) CORTEVA AGRISCIENCE LLC (US) 2022-12-14 EP claimed
US-20140274704-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF FOR USE IN CORN (MAIZE) DOW AGROSCIENCES LLC (US) 2014-09-18 US claimed
WO-2014061825-A1 TREATMENT OF VIRAL AND INFECTIOUS DISEASES USING AN INHIBITOR OF CBP/CATENIN KOUJI HIROYUKI (JP) 2014-04-24 WO claimed
CN-102307990-A Methods of deriving differentiated cells from stem cells INT STEM CELL CORP 2012-01-04 CN claimed
EP-2367931-A1 METHODS OF DERIVING DIFFERENTIATED CELLS FROM STEM CELLS International Stem Cell Corporation (US) 2011-09-28 EP claimed
US-20100173414-A1 Methods of Deriving Differentiated Cells from Stem Cells INTERNATIONAL STEM CELL CORPORATION (US) 2010-07-08 US claimed
WO-2010065679-A1 METHODS OF DERIVING DIFFERENTIATED CELLS FROM STEM CELLS INTERNATIONAL STEM CELL CORPORATION (US) 2010-06-10 WO claimed
US-20050026184-A1 Using serine/threoine kinases (ALK-7) as screening tools in identifying modulators for treatment of nervous system disorders SUGEN INC 2005-02-03 US claimed
CN-1310612-A Novel particulate formulations LIPOSOME CO INC (US) 2001-08-29 CN claimed
US-5672621-A CONTROLLING COLEOPTERAN (BEETLES) AND LEPIDOPTERAN (MOTHS); BIODEGRADABLE; NONTOXIC TO MAMMALS; METABOLITE ISOLATED FROM SCLEROTIA OF FUNGUS ASPERGILLUS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1997-09-30 US claimed
US-5519052-A INSECTICIDES USING PHENOLIC FURANONE DERIVATIVES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1996-05-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF DDT, HACL2, ALAD MAOA 196/4885MAOB 245/4885FTO 2188/4885
US-11672866-B2 Osteotropic nanoparticles for prevention or treatment of bone metastases SOST, ACP3, KLK3 MAOA 4428/4885MAOB 4405/4885FTO 4219/4885
US-20140274704-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF FOR USE IN CORN (MAIZE) DDT, DDC, DBF4 MAOA 897/4885MAOB 680/4885FTO 448/4885
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES WNT3A, GSK3B, GSK3A MAOA 3749/4885MAOB 2866/4885FTO 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.