SCHEMBL30189586

SCHEMBL30189586

O=C(O)C(=Cc1ccccc1)CC(O)CO

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
GRIK1 P39086 3/20 0.46
RECQL P46063 1/20 0.46
AKR1C3 P42330 1/20 0.44
AKR1C1 Q04828 1/20 0.43
MME P08473 2/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TP53 P04637 1/20 0.38
GRIK2 Q13002 1/20 0.38
OPRM1 P35372 1/20 0.38
HTT P42858 1/20 0.38
OPRK1 P41145 1/20 0.37
FBP1 P09467 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1633083 0.83 LMNA (0.43) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL10451936 0.80 CYP3A4 (0.58) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL21264081 0.80 CYP3A4 (0.58) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL1716474 0.80 CYP3A4 (0.58) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL2138074 0.80 CYP3A4 (0.62) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL5823755 0.79 CYP1A2 (0.37) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL5823757 0.79 CYP1A2 (0.37) CYP3A4CYP2C9GRIK1RECQLAKR1C3
Acetic Acid SCHEMBL28906961 0.79 LMNA (0.48) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL7101790 0.79 CYP3A4 (0.66) CYP3A4CYP2C9GRIK1RECQLAKR1C3
SCHEMBL261986 0.79 CYP3A4 (0.66) CYP3A4CYP2C9GRIK1RECQLAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof MEDIHELPLINE CO., LTD (KR) 2026-05-05 US disclosed
WO-2025105415-A1 MELANOGENESIS INHIBITOR AND EXTERNAL PREPARATION FOR SKIN CONTAINING SAME 三菱瓦斯化学株式会社 2025-05-22 WO disclosed
US-20230127213-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR THE TREATMENT OR ALLEVIATION OF SKIN ULCER AND THE USE THEREOF PARK, OK NAM (KR) 2023-04-27 US disclosed
US-20230103514-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR THE SKIN REGENERATION AND THE TREATMENT OR ALLEVIATION OF SKIN WOUND AND THE USE THEREOF MEDIHELPLINE CO., LTD (KR) 2023-04-06 US disclosed
US-20230100173-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR TLSP INHIBITION AND THE TREATMENT OR ALLEVIATION OF SKIN INFLAMMATORY DISEASE AND THE USE THEREOF MEDIHELPLINE CO., LTD (KR) 2023-03-30 US disclosed
EP-4117699-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR THE TREATMENT OR ALLEVIATION OF SKIN ULCER AND THE USE THEREOF Medihelpline Co., Ltd. (KR) 2023-01-18 EP disclosed
EP-4117698-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR THE SKIN REGENERATION AND THE TREATMENT OR ALLEVIATION OF SKIN WOUND AND THE USE THEREOF Medihelpline Co., Ltd. (KR) 2023-01-18 EP disclosed
EP-4117700-A1 A TOPICAL COMPOSITION COMPRISING AN EXTRACT OF COMBINED HERBS COMPRISING LONGANAE ARILLUS FOR TLSP INHIBITION AND THE TREATMENT OR ALLEVIATION OF SKIN INFLAMMATORY DISEASE AND THE USE THEREOF Medihelpline Co., Ltd. (KR) 2023-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616730-B2 Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof CUTA, VEGFA, MMP8 CYP3A4 3059/4885CYP2C9 2675/4885GRIK1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.