Sugi Predict

Sugi Predict / Compounds / SCHEMBL30193388

SCHEMBL30193388

SCHEMBL30193388

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nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 7/20 0.51
▸ NAALAD2 Q9Y3Q0 2/20 0.51
▸ RIMKLA Q8IXN7 1/20 0.51
▸ NOD1 Q9Y239 1/20 0.51
▸ MME P08473 2/20 0.44
▸ GNPAT O15228 1/20 0.43
▸ GABRP O00591 2/20 0.43
▸ GABRD O14764 2/20 0.43
▸ GABRA1 P14867 2/20 0.43
▸ GABRB1 P18505 2/20 0.43
▸ GABRG2 P18507 2/20 0.43
▸ GABRB3 P28472 2/20 0.43
▸ GABRA5 P31644 2/20 0.43
▸ GABRA3 P34903 2/20 0.43
▸ GABRA2 P47869 2/20 0.43
▸ GABRB2 P47870 2/20 0.43
▸ GABRA4 P48169 2/20 0.43
▸ GABRE P78334 2/20 0.43
▸ GABRA6 Q16445 2/20 0.43
▸ GABRG1 Q8N1C3 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30193512 1.00 FOLH1 (0.51) FOLH1NAALAD2RIMKLANOD1MME
SCHEMBL30381890 0.94 NOD1 (0.48) FOLH1NAALAD2RIMKLANOD1MME
SCHEMBL28727831 0.92 FOLH1 (0.56) FOLH1NAALAD2RIMKLANOD1GNPAT
SCHEMBL29517639 0.92 FOLH1 (0.56) FOLH1NAALAD2RIMKLANOD1GNPAT
SCHEMBL28727840 0.92 FOLH1 (0.56) FOLH1NAALAD2RIMKLANOD1GNPAT
SCHEMBL23044064 0.92 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL1270356 0.92 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL7762097 0.92 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL11188341 0.92 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP
SCHEMBL2490631 0.92 FOLH1 (0.60) FOLH1NAALAD2RIMKLANOD1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-11-07 — — US disclosed
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds SEAGEN INC. (US) 2024-07-16 — — US disclosed
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-06-27 — — US disclosed
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC. 2023-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ FOLH1 23/4885NAALAD2 77/4885RIMKLA 2396/4885
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ FOLH1 23/4885NAALAD2 77/4885RIMKLA 2396/4885
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds CTSB, CTSE, CTSZ FOLH1 23/4885NAALAD2 77/4885RIMKLA 2396/4885
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ FOLH1 23/4885NAALAD2 77/4885RIMKLA 2396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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