SCHEMBL3019809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9303544	0.83	ACACB (0.56)	ACACBAPPSLC6A2SLC6A4SLC6A3
	SCHEMBL3485737	0.83	ACACB (0.43)	ACACBGABRA5GABRA1GABRG2GABRB3
	SCHEMBL8960130	0.81	ACACB (0.31)	ACACBGABRA5GABRA1GABRG2GABRB3
	SCHEMBL8983744	0.81	ACACB (0.32)	ACACBGABRA5GABRA1GABRG2GABRB3
	SCHEMBL3846192	0.79	GRM5 (0.39)	ACACBGABRA5GABRA1GABRG2GABRB3
	SCHEMBL19297787	0.79	PREP (0.42)	GABRA5GABRA1GABRG2GABRB3GABRA3
	SCHEMBL1306384	0.78	GABRA1 (0.38)	GABRA5GABRA1GABRG2GABRB3GABRA3
	SCHEMBL673162	0.78	APP (0.55)	ACACBAPP
	SCHEMBL1306505	0.76	APP (0.41)	GABRA5GABRA1GABRG2GABRB3GABRA3
	SCHEMBL18245069	0.76	ACACB (0.46)	ACACBAPPRIPK1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.