Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019281 | 0.95 | HRH3 (0.35) | HRH3FABP4ALDH1A1 | |
| SCHEMBL3009855 | 0.94 | HRH3 (0.34) | HRH3FABP4ALDH1A1 | |
| SCHEMBL3013690 | 0.88 | FABP4 (0.37) | HRH3FABP4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3009892 | 0.87 | CACNA1G (0.37) | HRH3FABP4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3013257 | 0.87 | RIPK1 (0.33) | HRH3RIPK1 | |
| SCHEMBL3016736 | 0.86 | ALDH1A1 (0.37) | FABP4CACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL3014593 | 0.86 | CACNA1G (0.42) | HRH3FABP4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3004088 | 0.86 | ALDH1A1 (0.35) | HRH3FABP4ALDH1A1 | |
| SCHEMBL3018214 | 0.86 | CACNA1G (0.37) | HRH3FABP4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3013495 | 0.85 | DNM1L (0.33) | HRH3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722681-B2 | N-sulfonyl thiazolylpiperazine derivatives and related N-sulfonyl heterocyclic derivatives for the treatment of neuro degenerative diseases | NV REMYND (BE) | 2014-05-13 | — | — | US | disclosed |
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | NV REMYND (BE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197703-A1 | N-SULFONYL THIAZOLYLPIPERAZINE DERIVATIVES AND RELATED N-SULFONYL HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | SMN1; SMN2, HTT, SNCA | HRH3 2846/4885FABP4 3254/4885CACNA1G 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.