Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200470 | 0.87 | ALDH1A1 (0.48) | TAS2R14CXCR3PTGESTAS2R8ACHE | |
| SCHEMBL1616048 | 0.79 | TAS2R14 (0.58) | TAS2R14CXCR3PTGESTAS2R8ACHE | |
| SCHEMBL31626600 | 0.77 | LMNA (0.52) | LTA4HLMNA | |
| SCHEMBL6122068 | 0.75 | TRPM8 (0.48) | BMP1LTA4H | |
| SCHEMBL14072159 | 0.75 | ALDH1A1 (0.53) | LTA4HLMNA | |
| SCHEMBL30200699 | 0.74 | TAS2R14 (0.46) | TAS2R14CXCR3PTGESTAS2R8APLNR | |
| SCHEMBL305162 | 0.74 | MAPT (0.68) | LMNA | |
| SCHEMBL26023562 | 0.74 | MAPT (0.68) | LMNA | |
| SCHEMBL30200646 | 0.73 | ALDH1A1 (0.50) | TAS2R14CXCR3PTGESTAS2R8ACHE | |
| SCHEMBL7004788 | 0.73 | BMP1 (0.66) | TAS2R14CXCR3PTGESTAS2R8BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401729-A1 | BCL-XL DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023044046-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |