Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833231 | 0.83 | OPRK1 (0.39) | KCNH2OPRM1OPRD1OPRK1 | |
| SCHEMBL367111 | 0.69 | DRD2 (0.63) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL29423860 | 0.69 | DRD2 (0.63) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL12534041 | 0.67 | DRD2 (0.49) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL30201507 | 0.66 | KCNH2 (0.33) | KCNH2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL15856596 | 0.66 | OPRM1 (0.46) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL15008730 | 0.65 | SCD (0.52) | DRD2SLC6A4SCDKDM4EALDH1A1 | |
| SCHEMBL20669017 | 0.64 | DRD2 (0.49) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL12605572 | 0.63 | DRD2 (0.59) | DRD2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL3640167 | 0.63 | DRD2 (0.59) | DRD2SLC6A4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |