Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 3/20 | 0.32 |
| ▸ | ARG2 | P78540 | 3/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201500 | 0.81 | CYP3A4 (0.39) | ARG1ARG2HRH4HRH3ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30201414 | 0.73 | OPRM1 (0.51) | KCNH2MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.72 | LTA4H (0.49) | KCNH2MEN1KMT2AARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201373 | 0.72 | ARG1 (0.38) | KCNH2ARG1ARG2HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201490 | 0.72 | ARG1 (0.35) | KCNH2ARG1ARG2HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30201522 | 0.71 | ARG1 (0.37) | KCNH2MEN1KMT2AARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL31622406 | 0.71 | ARG1 (0.37) | KCNH2MEN1KMT2AARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201437 | 0.71 | ARG1 (0.54) | KCNH2MEN1KMT2AARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.71 | ARG1 (0.54) | KCNH2MEN1KMT2AARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.71 | LTA4H (0.48) | KCNH2MEN1KMT2AARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |