Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.33 |
| ▸ | KDM5C | P41229 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301387 | 0.87 | SLC22A6 (0.46) | LMNAOR51E2KMT2ASLC22A6AKR1B1 | |
| SCHEMBL17237871 | 0.77 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL11347415 | 0.76 | CES1 (0.42) | OR51E2KMT2ASLC22A6AKR1B1TSHR | |
| SCHEMBL11267132 | 0.74 | — | — | |
| SCHEMBL6272882 | 0.70 | EPHX2 (0.38) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| SCHEMBL25224556 | 0.70 | TSHR (0.50) | LMNAKDM4EKMT2ATSHRALDH1A1 | |
| SCHEMBL1285864 | 0.69 | — | — | |
| SCHEMBL1572411 | 0.68 | — | — | |
| SCHEMBL9303765 | 0.68 | ALDH1A1 (0.39) | ALDH1A1 | |
| Succinic Acid SCHEMBL156758 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403538-B1 | CONJUGATED PROTEINS AND PEPTIDES | POLYTHERICS LTD (GB) | 2017-10-04 | — | — | EP | disclosed |
| EP-2403538-B1 | CONJUGATED PROTEINS AND PEPTIDES | POLYTHERICS LTD (GB) | 2017-10-04 | — | — | EP | disclosed |
| US-9415115-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2016-08-16 | — | — | US | disclosed |
| US-9415115-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2016-08-16 | — | — | US | disclosed |
| US-9415115-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2016-08-16 | — | — | US | disclosed |
| US-20150216994-A1 | CONJUGATED PROTEINS AND PEPTIDES | ABZENA (CAMBRIDGE) LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150216994-A1 | CONJUGATED PROTEINS AND PEPTIDES | ABZENA (CAMBRIDGE) LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| US-20150216994-A1 | CONJUGATED PROTEINS AND PEPTIDES | ABZENA (CAMBRIDGE) LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| US-9005598-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-9005598-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-9005598-B2 | Conjugated proteins and peptides | POLYTHERICS LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-20120014905-A1 | CONUGATED PROTEINS AND PEPTIDES | POLYTHERICS LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120014905-A1 | CONUGATED PROTEINS AND PEPTIDES | POLYTHERICS LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| EP-2403538-A1 | CONJUGATED PROTEINS AND PEPTIDES | Polytherics Limited (GB) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100430-A1 | CONJUGATED PROTEINS AND PEPTIDES | POLYTHERICS LIMITED (GB) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216994-A1 | CONJUGATED PROTEINS AND PEPTIDES | CRKL, C1QBP, ARGLU1 | EGLN1 4033/4885LMNA 3037/4885ALKBH5 4858/4885 |
| US-20120014905-A1 | CONUGATED PROTEINS AND PEPTIDES | C1QBP, CHP1, MAN2A1 | EGLN1 3378/4885LMNA 1698/4885ALKBH5 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.