Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 5/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209215 | 1.00 | IMPDH2 (0.54) | IMPDH2ROCK2ROCK1KDM4EMEN1 | |
| SCHEMBL1568575 | 0.88 | IMPDH2 (0.68) | IMPDH2ROCK2ROCK1KDM4EALDH1A1 | |
| SCHEMBL1568741 | 0.84 | IMPDH2 (0.63) | IMPDH2ROCK2ROCK1KDM4EMEN1 | |
| SCHEMBL28304439 | 0.84 | IMPDH2 (0.50) | IMPDH2ROCK2ROCK1ALDH1A1PRMT3 | |
| Phenyl Phenylcarbamate SCHEMBL29668167 | 0.76 | ALDH1A1 (0.63) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL14124392 | 0.76 | ROCK2 (0.61) | IMPDH2ROCK2ALDH1A1PRMT3NOTUM | |
| SCHEMBL6630095 | 0.75 | IMPDH2 (0.64) | IMPDH2ROCK2ROCK1MEN1ALDH1A1 | |
| SCHEMBL20353459 | 0.75 | ROCK2 (0.57) | IMPDH2ROCK2ROCK1PRMT3NOTUM | |
| SCHEMBL20353458 | 0.75 | NOTUM (0.71) | IMPDH2ROCK2ROCK1KMT2APRMT3 | |
| SCHEMBL24969695 | 0.73 | ALDH1A1 (0.63) | KDM4EMEN1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956900-B | Compounds and pharmaceutical compositions comprising the same | 财团法人工业技术研究院 | 2023-02-03 | — | — | CN | disclosed |