SCHEMBL30209352

SCHEMBL30209352

Oc1cc(I)c(F)cc1F

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA3 P07451 2/20 0.40
CA9 Q16790 2/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
TTR P02766 1/20 0.33
HSD17B1 P14061 3/20 0.32
HSD17B2 P37059 3/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
ACHE P22303 1/20 0.31
BACE1 P56817 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21614392 1.00 CA3 (0.40) CA3CA9CA6CA5ACA14
SCHEMBL27047975 0.83 CA3 (0.35) CA3CA9CA6CA5ACA14
SCHEMBL19001649 0.78 CA1 (0.31) CA3CA9CA1CA2
SCHEMBL5511692 0.78 CA9 (0.50) CA3CA9CA6CA5ACA14
SCHEMBL23706706 0.77 CA3 (0.36) CA3CA9CA6CA5ACA14
SCHEMBL7665669 0.77 TSHR (0.46) CA3CA9CA6CA5ACA14
SCHEMBL2914174 0.77 KDM4E (0.42) CA3CA9CA6CA5ACA14
SCHEMBL27728509 0.77 ALDH1A1 (0.37) CA3CA9CA6CA5ACA14
SCHEMBL2934814 0.76 GPR84 (0.31) CA3CA9CA1CA2
SCHEMBL318772 0.76 CA9 (0.48) CA3CA9CA6CA5ACA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831337-B GLP-1 receptor agonist, and pharmaceutical composition and use thereof 广州市恒诺康医药科技有限公司 2023-03-24 CN disclosed