Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29689993 | 0.91 | HSD11B1 (0.72) | KMT2ARECQLHSD11B1ALDH1A1NPC1 | |
| SCHEMBL9548505 | 0.85 | HSD11B1 (0.71) | KMT2ARECQLHSD11B1CA12CA9 | |
| SCHEMBL30209481 | 0.81 | RECQL (0.63) | KMT2ARECQLHSD11B1CA12CA9 | |
| SCHEMBL2540768 | 0.80 | ALDH1A1 (0.50) | KMT2AALDH1A1IDO1TDO2MAPT | |
| SCHEMBL2422002 | 0.76 | RECQL (1.00) | KMT2ARECQLHSD11B1ALDH1A1MAPT | |
| SCHEMBL29609963 | 0.75 | RECQL (0.97) | KMT2ARECQLHSD11B1ALDH1A1MAPT | |
| SCHEMBL28497899 | 0.75 | HSD11B1 (0.76) | KMT2ARECQLHSD11B1ALDH1A1MAPT | |
| SCHEMBL29012562 | 0.74 | HSD11B1 (0.83) | KMT2ARECQLHSD11B1CA12CA9 | |
| SCHEMBL15979731 | 0.74 | CTNNB1 (0.65) | KMT2AIDO1TDO2NPC1LMNA | |
| SCHEMBL9414560 | 0.73 | POLB (0.68) | KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |