Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209489 | 0.81 | KMT2A (0.62) | RECQLHSD11B1POLBCA12CA9 | |
| SCHEMBL2422002 | 0.78 | RECQL (1.00) | RECQLHSD11B1ALDH1A1MAPTLMNA | |
| SCHEMBL29609963 | 0.76 | RECQL (0.97) | RECQLHSD11B1ALDH1A1MAPTLMNA | |
| SCHEMBL29012562 | 0.75 | HSD11B1 (0.83) | RECQLHSD11B1CA12CA9ALDH1A1 | |
| SCHEMBL29012568 | 0.75 | KMT2A (0.73) | RECQLHSD11B1CA9ALDH1A1MAPT | |
| SCHEMBL6202982 | 0.74 | HSD11B1 (1.00) | RECQLHSD11B1ALDH1A1MAPTLMNA | |
| SCHEMBL10872654 | 0.74 | RECQL (0.91) | RECQLHSD11B1ALDH1A1MAPTLMNA | |
| SCHEMBL30209484 | 0.74 | RECQL (0.68) | RECQLHSD11B1ALDH1A1MAPTLMNA | |
| SCHEMBL15979729 | 0.73 | PKM (0.62) | POLBPKMKMT2APTPN1ERCC5 | |
| SCHEMBL30209482 | 0.73 | HSD11B1 (0.82) | RECQLHSD11B1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |