SCHEMBL3020985

SCHEMBL3020985

Cc1cc(O)ccc1OCC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
FFAR4 Q5NUL3 1/20 0.51
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ESR1 P03372 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
MAPT P10636 1/20 0.46
ELANE P08246 3/20 0.45
F2 P00734 1/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
ABCB1 P08183 1/20 0.45
CASP3 P42574 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13342992 0.86 MAPT (0.59) MAPK1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL23447516 0.85 SMN1; SMN2 (0.68) MAPK1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL3017821 0.85 NPC1 (0.56) MAPK1NPC1RAB9ASMN1; SMN2FFAR4
SCHEMBL1549799 0.84 ESR1 (0.61) MEN1KMT2AALDH1A1ESR1KDM4E
SCHEMBL3018134 0.83 NPC1 (0.54) MAPK1NPC1RAB9ASMN1; SMN2FFAR4
SCHEMBL1285894 0.82 FFAR4 (0.61) MAPK1SMN1; SMN2FFAR4L3MBTL1MAPT
SCHEMBL3017737 0.80 ESR1 (0.54) RAB9AKMT2AALDH1A1L3MBTL1ESR1
SCHEMBL1245338 0.79 LMNA (0.50) RAB9AESR1MAPTKDM4ELMNA
SCHEMBL197583 0.79 PPARD (0.55) PPARGPPARDFFAR1
SCHEMBL3006259 0.78 ALDH1A1 (0.60) MAPK1NPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC 2010-08-05 US disclosed
EP-2029507-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES High Point Pharmaceuticals, LLC (US) 2009-03-04 EP disclosed
WO-2007141295-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HIGH POINT PHARMACEUTICALS, LLC (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197950-A1 PROCESS FOR PREPARING PHENOXY ACETIC ACID DERIVATIVES HAAO, HPD, PAH MAPK1 544/4885NPC1 4663/4885RAB9A 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.