Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211043 | 0.85 | SCN9A (0.60) | SCN9ATRPV1PTGS2PTGS1PTGES2 | |
| SCHEMBL1069769 | 0.82 | PTGES2 (0.42) | SCN9APTGS2PTGS1PTGES2CA1 | |
| SCHEMBL27702233 | 0.75 | CA2 (0.47) | PTGES2CA1CA2KIF11 | |
| SCHEMBL8631562 | 0.75 | TRPV1 (0.50) | SCN9ATRPV1PTGS2PTGS1PTGES2 | |
| SCHEMBL14572634 | 0.74 | SCN9A (0.47) | SCN9ATRPV1PTGS2PTGS1SCN10A | |
| SCHEMBL8631700 | 0.71 | TRPV1 (0.47) | SCN9ATRPV1PTGS2CA1CA2 | |
| SCHEMBL17840231 | 0.71 | GPR3 (0.50) | KIF11ABL1BCR | |
| SCHEMBL18118195 | 0.71 | PTGS2 (0.68) | PTGS2PTGS1CA1CA2KIF11 | |
| SCHEMBL5518064 | 0.70 | SLC6A4 (0.55) | SCN9APTGES2SCN10ACA1CA2 | |
| SCHEMBL12952695 | 0.70 | KIF11 (0.40) | SCN9ATRPV1PTGS2PTGS1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |