Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656356 | 0.82 | CA12 (0.51) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3656353 | 0.81 | CA12 (0.44) | CA12CA1CA2CA4CA9 | |
| SCHEMBL15941568 | 0.78 | TP53 (0.59) | PLA2G4BPLA2G4ACA12CA1CA2 | |
| SCHEMBL3025585 | 0.78 | RARB (0.49) | PLA2G4BCA12CA1CA2CA4 | |
| SCHEMBL3026943 | 0.78 | CA12 (0.59) | PLA2G4BPLA2G4ACA12CA1CA2 | |
| SCHEMBL1018124 | 0.75 | CA2 (0.54) | PLA2G2APLA2G4BPLA2G4ACA12CA1 | |
| SCHEMBL13236608 | 0.75 | PLA2G2A (0.47) | PLA2G2APLA2G4BPLA2G4AKMT2AALDH1A1 | |
| SCHEMBL23927597 | 0.74 | TDP1 (0.47) | PLA2G4BCA12CA1CA2CA4 | |
| SCHEMBL10876734 | 0.74 | PLA2G4B (0.53) | PLA2G2APLA2G4BPLA2G4AALDH1A1SMN1; SMN2 | |
| SCHEMBL3030975 | 0.74 | PLA2G2A (0.48) | PLA2G2APLA2G4BPLA2G4ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| EP-2200967-A2 | NEW NO-DONOR ASPIRIN DERIVATIVES | Nicox S.A. (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009049961-A2 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | PTGIS, NOS2, NOS3 | PLA2G2A 1398/4885PLA2G4B 561/4885PLA2G4A 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.