Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027889 | 0.81 | PSMD14 (0.59) | PSMD14GABRA2GABRB2NR1I2ABCB11 | |
| SCHEMBL3022537 | 0.80 | GABRA2 (0.66) | PSMD14GABRA2GABRB2NR1I2ABCB11 | |
| Acetamide SCHEMBL3026879 | 0.79 | PSMD14 (0.58) | PSMD14GABRA2GABRB2NR1I2ABCB11 | |
| SCHEMBL17718869 | 0.77 | SLC2A1 (1.00) | ALDH1A1SLC2A1POLBKDM4ENPC1 | |
| SCHEMBL15331333 | 0.75 | PSMD14 (0.53) | ALDH1A1PSMD14POLBKDM4ENPC1 | |
| SCHEMBL3026882 | 0.70 | PSMD14 (0.48) | ALDH1A1PSMD14SLC2A1POLBHTT | |
| SCHEMBL1430426 | 0.69 | SLC2A1 (0.59) | ALDH1A1SLC2A1KDM4EHTTGABRA2 | |
| SCHEMBL1692145 | 0.69 | ALDH1A1 (0.58) | ALDH1A1SLC2A1KDM4EHTTGABRA2 | |
| SCHEMBL2792359 | 0.68 | ALDH1A1 (0.68) | ALDH1A1SLC2A1POLBKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL1430111 | 0.68 | SLC2A1 (0.58) | ALDH1A1SLC2A1KDM4EHTTGABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752415-B1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECH ORGANISATION (AU) | 2017-10-11 | — | — | EP | disclosed |
| EP-2752415-A1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2014-07-09 | — | — | EP | disclosed |
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | GABRA6, GABRA1, GABRA2 | ALDH1A1 1948/4885PSMD14 4214/4885SLC2A1 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.