Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302170 | 0.89 | LMNA (0.53) | LMNAALDH1A1MEN1KMT2ANR1I2 | |
| SCHEMBL302171 | 0.82 | MAPT (0.52) | LMNAALDH1A1KMT2AGAAHTT | |
| SCHEMBL1964511 | 0.81 | MEN1 (0.62) | LMNAALDH1A1MEN1KMT2ANR1I2 | |
| SCHEMBL2212915 | 0.75 | MEN1 (0.58) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL302890 | 0.72 | HTT (0.51) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2189346 | 0.72 | LMNA (0.85) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3274287 | 0.70 | KMT2A (0.60) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6562153 | 0.70 | ALDH1A1 (0.47) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1937572 | 0.70 | LMNA (0.55) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1967123 | 0.70 | LMNA (0.68) | LMNAALDH1A1MEN1KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500835-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | claimed |
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |